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Chronic-phase chronic myeloid leukemia: Incidence of BCR/ABL transcript and its correlation with presenting features, response to treatment, and survival

Introduction: Chronic myeloid leukemia (CML) is characterized by Philadelphia chromosome resulting in the fusion between the BCR gene, located on chromosome 22, and the ABL gene on chromosome 9. The prognostic significance of BCR-ABL transcript variants in CML is controversial. The aim of the curren...

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Principais autores: Baraa Laabidi, Nader Slama, Ines Ouahchi, Wiem Boufrikha, Mohamed Adnene Laatiri
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-01-01
coleção:Leukemia Research Reports
Assuntos:
Myeloproliferative disorder
Chronic phase
Philadelphia chromosome
BCR-ABL transcript
Imatinib mesylate
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213048923000134
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