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Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions

Background and Objectives P-selectin has been implicated in important platelet functions. However, neither its role in thrombus formation and cardiovascular disorders nor its suitability as a therapeutic target structure is entirely clear.Design and Methods Platelet aggregation was assessed in compl...

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Hlavní autoři: Gertie J. Oostingh, Miroslava Pozgajova, Ralf J. Ludwig, Thomas Krahn, W.-Henning Boehncke, Bernhard Nieswandt, Michael P. Schön
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2007-04-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/4402
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