Metabolite profile in hereditary spastic paraplegia analyzed using magnetic resonance spectroscopy: a cross-sectional analysis in a longitudinal study

BackgroundHereditary Spastic Paraplegias (HSP) are genetic neurodegenerative disorders affecting the corticospinal tract. No established neuroimaging biomarker is associated with this condition.MethodsA total of 46 patients affected by HSP, genetically and clinically evaluated and tested with SPRS s...

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Autors principals:	Domenico Montanaro, Marinela Vavla, Francesca Frijia, Alessio Coi, Alessandra Baratto, Rosa Pasquariello, Cristina Stefan, Andrea Martinuzzi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-08-01
Col·lecció:	Frontiers in Neuroscience
Matèries:	hereditary spastic paraplegias (HSP) magnetic resonance spectroscopy (MRS) cross sectional analysisis longitudinal analysis pre-frontal SPRS
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1416093/full
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