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Association study between immune-related miRNAs and mixed connective tissue disease

Abstract Background Mixed connective tissue disease (MCTD) is a rare condition that is distinguished by the presence of specific U1-RNP antibodies. Information about its etiopathology and diagnostics is still unclear. miRNAs such as miR-146, miR-155, and miR-143 emerged as key regulators of the immu...

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Principais autores: Barbara Stypińska, Aleksandra Lewandowska, Anna Felis-Giemza, Marzena Olesińska, Agnieszka Paradowska-Gorycka
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-01-01
coleção:Arthritis Research & Therapy
Assuntos:
MCTD
MicroRNA
Single-nucleotide polymorphisms
SNPs
Pathogenesis
Epigenetics
Acesso em linha:https://doi.org/10.1186/s13075-020-02403-9
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