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Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major.

Inflammatory monocytes can be manipulated by environmental cues to perform multiple functions. To define the role of monocytes during primary or secondary infection with an intra-phagosomal pathogen we employed Leishmania major-red fluorescent protein (RFP) parasites and multi-color flow cytometry t...

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Bibliografische Detailangaben
Hauptverfasser: Audrey Romano, Matheus B H Carneiro, Nicole A Doria, Eric H Roma, Flavia L Ribeiro-Gomes, Ehud Inbar, Sang Hun Lee, Jonatan Mendez, Andrea Paun, David L Sacks, Nathan C Peters
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2017-06-01
Schriftenreihe:PLoS Pathogens
Online-Zugang:https://doi.org/10.1371/journal.ppat.1006479
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