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Nucleic acid direct delivery to fibroblasts: a review of nucleofection and applications

Abstract The fibroblast is one of the ideal target cell candidates for cell-based gene therapy approaches to promote tissue repair. Gene delivery to fibroblasts by viral transfection has been confirmed to have high transfection efficiency. However, in addition to immunogenic effects of viruses, the...

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Autori principali: Ranyue Ren, Jiachao Guo, Guangwu Liu, Hao Kang, Hans-Günther Machens, Arndt F. Schilling, Alex Slobodianski, Ziyang Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-11-01
Serie:Journal of Biological Engineering
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Accesso online:https://doi.org/10.1186/s13036-022-00309-5
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