Red blood cell transfusion survival in sickle cell disease is reduced by donor characteristics and recipient spleen activity

Abstract: Red blood cell (RBC) transfusion therapy in sickle cell disease (SCD) is used to treat and prevent disease complications by providing nonsickle erythrocytes that survive for weeks in circulation. The suppression of sickle hemoglobin between transfusion episodes is dependent on donor RBC su...

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Principais autores:	Marianne E. M. Yee, Patricia E. Zerra, Richard O. Francis, Kirk A. Easley, Christopher M. Lough, James W. McCoy, Zahra Naseh, Bhaveshkumar B. Delvadia, Ashishkumar K. Parikh, Hailly E. Butler, Sean R. Stowell, Clinton H. Joiner, Cassandra D. Josephson, John D. Roback, Ross M. Fasano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-07-01
coleção:	Blood Advances
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2473952926003198
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