Progesterone receptor potentiates macropinocytosis through CDC42 in pancreatic ductal adenocarcinoma
Abstract Endocrine receptors play an essential role in tumor metabolic reprogramming and represent a promising therapeutic avenue in pancreatic ductal adenocarcinoma (PDAC). PDAC is characterized by a nutrient-deprived microenvironment. To meet their ascendant energy demands, cancer cells can intern...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2024-02-01
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| Serier: | Oncogenesis |
| Online adgang: | https://doi.org/10.1038/s41389-024-00512-7 |
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