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Characterization of CPH:SA microparticle‐based delivery of interleukin‐1 alpha for cancer immunotherapy

Abstract Background Interleukin‐1 alpha (IL‐1α) is a pro‐inflammatory cytokine that can activate immune effector cells and trigger anti‐tumor immune responses. However, dose‐limiting toxicities including cytokine storm and hypotension has limited its use in the clinic as a cancer therapy. We propose...

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Detalles Bibliográficos
Principais autores: M. M. Hasibuzzaman, Rui He, Ishrat Nourin Khan, Rasna Sabharwal, Aliasger K. Salem, Andrean Llewela Simons‐Burnett
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2023-05-01
Series:Bioengineering & Translational Medicine
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Acceso en liña:https://doi.org/10.1002/btm2.10465
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