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Subclinical epileptiform discharges in Alzheimer’s disease are associated with increased hippocampal blood flow

Abstract Background In epilepsy, the ictal phase leads to cerebral hyperperfusion while hypoperfusion is present in the interictal phases. Patients with Alzheimer’s disease (AD) have an increased prevalence of epileptiform discharges and a study using intracranial electrodes have shown that these ar...

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Автори: Christian Sandøe Musaeus, Troels Wesenberg Kjaer, Ulrich Lindberg, Mark B. Vestergaard, Henrik Bo, Wiberg Larsson, Daniel Zvi Press, Birgitte Bo Andersen, Peter Høgh, Preben Kidmose, Martin Christian Hemmsen, Mike Lind Rank, Steen Gregers Hasselbalch, Gunhild Waldemar, Kristian Steen Frederiksen
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2024-04-01
Серія:Alzheimer’s Research & Therapy
Предмети:
Alzheimer’s disease
Hyperperfusion
Epileptiform discharges
Spike frequency
EEG
Онлайн доступ:https://doi.org/10.1186/s13195-024-01432-9
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