Fast assay to predict multipotent mesenchymal stromal cell replicative senescence dynamics

The major obstacle to the application of mesenchymal stromal cells (MSCs) in regenerative medicine is the expansion of the donor-derived cells in vitro to obtain high cell numbers in the shortest possible time. However, MSCs gradually undergo replicative senescence after a variable number of divisio...

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Hlavní autoři:	Katja Kološa, Aleš Leskovšek, Teja Rajar, Tamara Lah
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2022-03-01
Edice:	BioTechniques
Témata:	adipose mesenchymal stromal (stem) cells (ASCs) cell longevity induced senescence mesenchymal stromal (stem) cells (MSCs) mitoxantrone replicative senescence
On-line přístup:	https://www.future-science.com/doi/10.2144/btn-2021-0087
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