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Inhibitors of sterol synthesis. Spectral characterization of derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one

Described herein are the chemical syntheses of a number of deuterated derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one. These include the [2,2,3 alpha,4,4,7,7,9 alpha,16,16-2H10]-, [7 alpha,9 alpha,16,16-2H4]-, [7,7,9 alpha,16,16-2H5]-, and [2,2,3 alpha,4,4-2H5]-analogs of the delta 8(14)-15...

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Detalles Bibliográficos
Principais autores: J St Pyrek, W K Wilson, G J Schroepfer, Jr
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 1987-11-01
Series:Journal of Lipid Research
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0022227520385941
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