The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation

Abstract Anticopalic acid (ACP), a labdane type diterpenoid obtained from Kaempferia elegans rhizomes, together with 21 semi-synthetic derivatives, were evaluated for their cancer cytotoxic activity. Most derivatives displayed higher cytotoxic activity than the parent compound ACP in a panel of nine...

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Autori principali:	Pornsuda Chawengrum, Natthaorn Luepongpatthana, Sanit Thongnest, Jitnapa Sirirak, Jutatip Boonsombat, Kriengsak Lirdprapamongkol, Siriporn Keeratichamroen, Patcharin Kongwaen, Phreeranat Montatip, Prasat Kittakoop, Jisnuson Svasti, Somsak Ruchirawat
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2023-08-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-023-40669-6
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