The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner

ObjectivesN6-methyladenosine (m6A) RNA methylation is implicated in the progression of multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in gastric cancer (GC), while the biological mechanisms via which YTHDF1 regulates gastric tumorigenesis through m6A modification r...

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Autores principales:	Xiao-Yu Chen, Rui Liang, You-Cai Yi, Hui-Ning Fan, Ming Chen, Jing Zhang, Jin-Shui Zhu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2021-03-01
Colección:	Frontiers in Cell and Developmental Biology
Materias:	tumorigenesis N6-methyladenosine metastasis gastric cancer YTHDF1 USP14
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcell.2021.647702/full
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