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The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

<p>Abstract</p> <p>Background</p> <p>The activity of the ribonucleoprotein enzyme telomerase is detectable in germ, stem and tumor cells. One major component of telomerase is human telomerase reverse transcriptase (hTERT), which encodes the catalytic subunit of telomerase. Here we investigate the co...

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Principais autores: Schulze Wolfgang, Schostak Martin, Straub Bernd, Krause Hans, Müller Markus, Burger Angelika M, Schrader Mark, Lauke Heidrun, Miller Kurt
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2002-11-01
Serier:BMC Cancer
Fag:
Telomerase activity
human telomerase reverse transcriptase
testicular germ cell tumors
Online adgang:http://www.biomedcentral.com/1471-2407/2/32
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