Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

Abstract Female adnexal malignancies, while relatively uncommon, exhibit high mortality rates due to often-late diagnosis. The serine/threonine kinase 11 (STK11) is a tumor suppressor gene, and its inactivation or mutation often leads to an autosomal dominant genetic disorder known as Peutz-Jeghers...

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Autores principales:	Guanxiang Huang, Wenyu Lin, Tingting Jiang, Yuanjun Cai, Chengbin Lin, Pengming Sun
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-03-01
Colección:	Human Genomics
Materias:	Serine/threonine kinase 11 Gynecological oncology Genetic susceptibility
Acceso en línea:	https://doi.org/10.1186/s40246-025-00741-w
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