Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)

Abstract Background Microglia-driven cerebral spreading inflammation is a key contributor to secondary brain injury after SAH. Genetic depletion or deactivation of microglia has been shown to ameliorate neuronal cell death. Therefore, clinically feasible anti-inflammatory approaches counteracting mi...

Полное описание

Библиографические подробности

Главные авторы:	Rebecca Heinz, Susan Brandenburg, Melina Nieminen-Kelhä, Irina Kremenetskaia, Philipp Boehm-Sturm, Peter Vajkoczy, Ulf C. Schneider
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2021-01-01
Серии:	Journal of Neuroinflammation
Предметы:	Subarachnoid hemorrhage, Inflammation, Microglia, Secondary brain injury, Inflammatory preconditioning, CSF1-Receptor
Online-ссылка:	https://doi.org/10.1186/s12974-021-02085-3
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!