Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia

Abstract Background The autonomic nervous system can modulate the innate immune responses to bacterial infections via the splanchnic sympathetic nerves. Here, we aimed to determine the effects of bilateral splanchnic sympathetic nerve denervation on blood pressure, plasma cytokines, blood bacterial...

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Detalhes bibliográficos

Principais autores:	Rachel M. Peiris, Clive N. May, Lindsea C. Booth, Robin M. McAllen, Michael J. McKinley, Sally Hood, Davide Martelli, Rinaldo Bellomo, Yugeesh R. Lankadeva
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2023-08-01
coleção:	Intensive Care Medicine Experimental
Assuntos:	Bacteremia Sepsis Splanchnic sympathetic nerves Cytokines Inflammation
Acesso em linha:	https://doi.org/10.1186/s40635-023-00530-6
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