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Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma

Abstract Background Gliosarcoma (GSM) is a distinct and aggressive variant of glioblastoma multiforme (GBM) with worse prognosis and few treatment options. It is often managed with the same treatment modalities with temozolomide (TMZ) as in GBM. However, the therapeutic benefits on GSM from such tre...

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Principais autores: Karrie Mei-Yee Kiang, Andrian A. Chan, Gilberto Ka-Kit Leung
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-03-01
Serier:BMC Cancer
Fag:
Gliosarcoma
Secondary gliosarcoma
Glioblastoma multiforme
Patient-derived xenograft
Primary culture
Online adgang:https://doi.org/10.1186/s12885-021-08008-y
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