Proteomics of Urinary Extracellular Vesicles Highlight the Involvement of Vitronectin and the Fibrinolytic and TNF Pathways as Mechanisms Underlying Renal Fibrosis in Kidney Transplant Patients

ABSTRACT Vitronectin (VTN) is a potential non‐invasive biomarker for renal fibrosis, originally described in urinary extracellular vesicles (uEV) from kidney transplant patients (KTx). However, VTN's specific role in renal fibrosis is unclear, as it is involved in various physiological processes. Th...

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Detalhes bibliográficos

Principais autores:	Marta Clos‐Sansalvador, Sergio G. Garcia, Paula Rodríguez‐Martínez, Marta Sanroque‐Muñoz, Miriam Font‐Morón, Cristina Grange, Benedetta Bussolati, Marcella Franquesa, Javier Juega, Francesc E. Borràs
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-06-01
coleção:	Journal of Extracellular Biology
Assuntos:	fibrinolysis proximity extension assay renal fibrosis TNF urinary extracellular vesicles vitronectin
Acesso em linha:	https://doi.org/10.1002/jex2.70056
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