The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential.

During 2015-2016, outbreaks of Zika virus (ZIKV) occurred in Southeast Asia and the Americas. Most ZIKV infections in humans are asymptomatic, while clinical manifestation is usually a self-limiting febrile disease with maculopapular rash. However, ZIKV is capable of inducing a range of severe neuro...

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Библиографические подробности

Главные авторы:	Nias Y G Peng, Alberto A Amarilla, Leon E Hugo, Naphak Modhiran, Julian D J Sng, Andrii Slonchak, Daniel Watterson, Yin Xiang Setoh, Alexander A Khromykh
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2022-05-01
Серии:	PLoS Neglected Tropical Diseases
Online-ссылка:	https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010426&type=printable
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