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Campylobacter jejuni pdxA affects flagellum-mediated motility to alter host colonization.

Vitamin B6 (pyridoxal-5'-phosphate, PLP) is linked to a variety of biological functions in prokaryotes. Here, we report that the pdxA (putative 4-hydroxy-L-threonine phosphate dehydrogenase) gene plays a pivotal role in the PLP-dependent regulation of flagellar motility, thereby altering host coloni...

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Autors principals: Hiroshi Asakura, Noritaka Hashii, Masashi Uema, Nana Kawasaki, Yoshiko Sugita-Konishi, Shizunobu Igimi, Shigeki Yamamoto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3735588?pdf=render
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