Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation

Hyper-inflammation during acute phase and sequential hypo-inflammation during immunosuppressive phase in macrophages/monocytes lead to multiorgan failure syndrome and immune collapse of sepsis, in which toll-like receptor (TLR)-triggered inflammatory responses play a major role. Here, we reported th...

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Egile Nagusiak:	Wenqian Li, Yinjiao Li, Kewei Qin, Boxiang Du, Tianliang Li, Hongbin Yuan, Chaofeng Han, Yan Luo
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2019-11-01
Saila:	Frontiers in Immunology
Gaiak:	Siglec-G Src homology region 2 domain-containing phosphatase-1 Src sepsis pro-inflammatory cytokines anti-inflammatory cytokine
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02575/full
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