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Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway

Primary hepatic carcinoma is a common malignant tumor. The classic molecular targeted drug sorafenib is costly and is only effective for some patients. Therefore, it is of great clinical significance to search for new molecular targeted drugs. Eupalinolide B (EB) from Eupatorium lindleyanum DC. is u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Prif Awduron: Zhang Yonghui, Zhang Haoyang, Mu Jinage, Han Meiyue, Cao Zhihao, Dong Feng, Wang Tingting, Pan Lian, Luo Wujing, Li Jiaxin, Liu Huan, Jin Lishan, Ding Wenxuan, Wei Yong, Deng Xuesong, Liu Dan, He Xiuzhen, Pang Yi, Mu Xiao, Wu Zhongjun, Chen Dilong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: China Science Publishing & Media Ltd. 2022-07-01
Cyfres:Acta Biochimica et Biophysica Sinica
Pynciau:
Eupalinolide B
hepatic carcinoma
ferroptosis
HO-1
ER stress
JNK
Mynediad Ar-lein:https://www.sciengine.com/doi/10.3724/abbs.2022082
Tagiau: Ychwanegu Tag
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