Effect of a loss of the mda5/ifih1 gene on the antiviral resistance in a Chinook salmon Oncorhynchus tshawytscha cell line.

Cells are equipped with intracellular RIG-like Receptors (RLRs) detecting double stranded (ds)RNA, a molecule with Pathogen-Associated Molecular Pattern (PAMPs) generated during the life cycle of many viruses. Melanoma Differentiation-Associated protein 5 (MDA5), a helicase enzyme member of the RLRs...

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Principais autores:	Catherine Collins, Lise Chaumont, Mathilde Peruzzi, Nedim Jamak, Pierre Boudinot, Julia Béjar, Patricia Moreno, Daniel Álvarez Torres, Bertrand Collet
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2024-01-01
Serija:	PLoS ONE
Online dostop:	https://doi.org/10.1371/journal.pone.0311283
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