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The CD8+ and CD4+ T Cell Immunogen Atlas of Zika Virus Reveals E, NS1 and NS4 Proteins as the Vaccine Targets

Zika virus (ZIKV)-specific T cells are activated by different peptides derived from virus structural and nonstructural proteins, and contributed to the viral clearance or protective immunity. Herein, we have depicted the profile of CD8+ and CD4+ T cell immunogenicity of ZIKV proteins in C57BL/6 (H-2...

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Principais autores: Hangjie Zhang, Wenling Xiao, Min Zhao, Yingze Zhao, Yongli Zhang, Dan Lu, Shuangshuang Lu, Qingxu Zhang, Weiyu Peng, Liumei Shu, Jie Zhang, Sai Liu, Kexin Zong, Pengyan Wang, Beiwei Ye, Shihua Li, Shuguang Tan, Fuping Zhang, Jianfang Zhou, Peipei Liu, Guizhen Wu, Xuancheng Lu, George F. Gao, William J. Liu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-10-01
Serier:Viruses
Fag:
Zika virus
T cells
immunodominance
peptide
epitope
Online adgang:https://www.mdpi.com/1999-4915/14/11/2332
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