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A Bifunctional Molecule with Lectin and Protease Inhibitor Activities Isolated from <i>Crataeva tapia</i> Bark Significantly Affects Cocultures of Mesenchymal Stem Cells and Glioblastoma Cells

Currently available drugs for treatment of glioblastoma, the most aggressive brain tumor, remain inefficient, thus a plethora of natural compounds have already been shown to have antimalignant effects. However, these have not been tested for their impact on tumor cells in their microenvironment-simu...

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Autori principali: Camila Ramalho Bonturi, Mariana Cristina Cabral Silva, Helena Motaln, Bruno Ramos Salu, Rodrigo da Silva Ferreira, Fabricio Pereira Batista, Maria Tereza dos Santos Correia, Patrícia Maria Guedes Paiva, Tamara Lah Turnšek, Maria Luiza Vilela Oliva
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-06-01
Serie:Molecules
Soggetti:
CrataBL
glioblastoma
mesenchymal stem cells
microenvironment
plant lectin
protease inhibitor
Accesso online:https://www.mdpi.com/1420-3049/24/11/2109
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