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Organoid-based profiling identifies TGFB1 and PADI2 as key modulators of pancreatic cancer growth

Objective:. This study aimed to systematically evaluate the effects of human cytokines on the growth and transcriptional regulation of pancreatic ductal adenocarcinoma (PDAC) cells, using 3D tumor spheroid models to identify key cytokine–gene interactions relevant to tumor progression. Methods:. Hum...

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Auteurs principaux: Ruoxi Zhang, Chunhua Yu, Daolin Tang, Rui Kang
Format: Artigo
Langue:Inglês
Publié: Wolters Kluwer Health/LWW 2026-03-01
Collection:Journal of Pancreatology
Accès en ligne:http://journals.lww.com/10.1097/JP9.0000000000000248
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