Efficacy of phytochemicals derived from Artocarpus heterophyllus (Jackfruit) as inhibitors against NS2B/NS3 protease of dengue virus: an in-silico investigation

Abstract Dengue virus is one of the most significant emerging viruses that cause dengue fever, dengue hemorrhagic disease and dengue shock syndrome, threatening one-third of the world’s population. There are currently no vaccinations or antiviral therapies available for this disease. Dengue virus pr...

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Principais autores:	Mohammad Abu Raihan Uddin, Apon Chandra Paul, Md Shariful Islam, Sourav Dev Nath, Israt Jahan Mim, Md Imon Hossain, Wan Nor Fazila Hafizan Wan Nik, Nurul Absar, Tuan Salwani Tuan Ismail, Rizone Al Hasib, Mohammad Abu Hena Mostofa Jamal
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
coleção:	Scientific Reports
Assuntos:	Dengue virus NS2B/NS3 protease Artocarpus heterophyllus Virtual screening Antiviral drug discovery
Acesso em linha:	https://doi.org/10.1038/s41598-026-38726-x
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