Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function

Inhibitory natural killer (NK) cell receptors recognize MHC class I (MHC-I) in trans on target cells and suppress cytotoxicity. Some NK cell receptors recognize MHC-I in cis, but the role of this interaction is uncertain. Ly49Q, an atypical Ly49 receptor expressed in non-NK cells, binds MHC-I in cis...

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書誌詳細

主要な著者:	Hitomi Karyu, Takahiro Niki, Yuriko Sorimachi, Shoji Hata, Shiho Shimabukuro-Demoto, Tetsuya Hirabayashi, Kojiro Mukai, Kohji Kasahara, Keiyo Takubo, Nobuhito Goda, Koichi Honke, Tomohiko Taguchi, Hiroyuki Sorimachi, Noriko Toyama-Sorimachi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2024-04-01
シリーズ:	Frontiers in Immunology
主題:	inhibitory receptor Ly49 MHC class I cis interaction sphingolipids 2 phagocytosis
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1401294/full
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