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The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells

Abstract Human natural killer (NK) cells are cytotoxic effector cells that are increasingly harnessed in cancer immunotherapy. NKG2A/CD94 is an inhibitory receptor on NK cells that has established regulatory functions in the direct interaction with target cells when engaged with its ligand, the non-...

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Principais autores: Meike Kaulfuss, Juliane Mietz, Astrid Fabri, Johannes vom Berg, Christian Münz, Obinna Chijioke
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2023-06-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-023-37779-6
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