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Nitrate-mediated luminal expansion of Salmonella Typhimurium is dependent on the ER stress protein CHOP

ABSTRACT Salmonella Typhimurium (S. Typhimurium) is an enteric pathogen that employs a variety of mechanisms to exploit inflammation, resulting in expansion in the intestinal tract, but host factors that contribute to or counteract the luminal expansion are not well-defined. Endoplasmic reticulum (E...

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Main Authors: Elizabeth A. Alexander, Lydia A. Sweet, Sharon K. Kuss-Duerkop, Mariana X. Byndloss, Tamarah E. Schaberg, A. Marijke Keestra-Gounder
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2026-07-01
Series:mBio
Subjects:
Salmonella
innate immunity
CHOP
Online Access:https://journals.asm.org/doi/10.1128/mbio.01008-26
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