Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

Drug resistance is a commonly unavoidable consequence of cancer treatment that results in therapy failure and disease relapse. Intrinsic (pre-existing) or acquired resistance mechanisms can be drug-specific or be applicable to multiple drugs, resulting in multidrug resistance. The presence of drug r...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ronay Cetin, Eva Quandt, Manuel Kaulich
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-01-01
Schriftenreihe:	Cells
Schlagworte:	chemotherapy resistance cancer and drug vulnerabilities functional genomics RNAi and CRISPR screens
Online-Zugang:	https://www.mdpi.com/2073-4409/10/2/260
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