An effective processing pipeline for harmonizing DNA methylation data from Illumina’s 450K and EPIC platforms for epidemiological studies

Abstract Objective Illumina BeadChip arrays are commonly used to generate DNA methylation data for large epidemiological studies. Updates in technology over time create challenges for data harmonization within and between studies, many of which obtained data from the older 450K and newer EPIC platfo...

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Hauptverfasser:	Lauren A. Vanderlinden, Randi K. Johnson, Patrick M. Carry, Fran Dong, Dawn L. DeMeo, Ivana V. Yang, Jill M. Norris, Katerina Kechris
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-09-01
Schriftenreihe:	BMC Research Notes
Schlagworte:	DNA methylation Illumina 450K Illumina EPIC Platform harmonization
Online-Zugang:	https://doi.org/10.1186/s13104-021-05741-2
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