Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition

Abstract Background Cartilage oligomeric matrix protein (COMP), an extracellular matrix glycoprotein, is vital in preserving cartilage integrity. Further, its overexpression is associated with the aggressiveness of several types of solid cancers. This study investigated COMP’s role in ovarian cancer...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Gilar Gorji-Bahri, B. Madhu Krishna, Catharina Hagerling, Akira Orimo, Karin Jirström, Konstantinos S. Papadakos, Anna M. Blom
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2024-04-01
Σειρά:	Journal of Translational Medicine
Θέματα:	Ovarian cancer Stroma COMP CAF Epithelial-to-mesenchymal transition
Διαθέσιμο Online:	https://doi.org/10.1186/s12967-024-05083-0
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