Direct and Efficient C(sp3)–H Functionalization of N-Acyl/Sulfonyl Tetrahydroisoquinolines (THIQs) With Electron-Rich Nucleophiles via 2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone (DDQ) Oxidation

A highly efficient metal-free oxidative direct C(sp3)–H functionalization of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) with a wide range of electron-rich nucleophiles was accomplished under mild conditions through oxidation with DDQ and subsequent trapping of the resulting reactive and...

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Bibliografski detalji

Glavni autori:	Heesun Yu, Hyoungsu Kim, Seung-Hoon Baek, Dongjoo Lee
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2020-07-01
Serija:	Frontiers in Chemistry
Teme:	tetrahydroisoquinoline oxidation DDQ electron-rich natural products
Online pristup:	https://www.frontiersin.org/article/10.3389/fchem.2020.00629/full
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