Development and Optimization of Nanolipid-Based Formulation of Diclofenac Sodium: In Vitro Characterization and Preclinical Evaluation

In the present research study, we formulate bilosomes (BMs) of diclofenac (DC) for oral delivery for enhancement of therapeutic efficacy (anti-inflammatory disease). The BMS were prepared by thin film hydration method and optimized by Box–Behnken design (BBD) using cholesterol (A), lipid (B), surfac...

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Autores principales:	Ameeduzzafar Zafar, Nabil K Alruwaili, Syed Sarim Imam, Mohd Yasir, Omar Awad Alsaidan, Ali Alquraini, Alenazy Rawaf, Bader Alsuwayt, Md. Khalid Anwer, Sultan Alshehri, Mohammed M. Ghoneim
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-02-01
Colección:	Pharmaceutics
Materias:	bilosomes diclofenac optimization pharmacokinetic pharmacodynamic study
Acceso en línea:	https://www.mdpi.com/1999-4923/14/3/507
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