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A Genetically Encoded Bioluminescence Intracellular Nanosensor for Androgen Receptor Activation Monitoring in 3D Cell Models

In recent years, there has been an increasing demand for predictive and sensitive in vitro tools for drug discovery. Split complementation assays have the potential to enlarge the arsenal of in vitro tools for compound screening, with most of them relying on well-established reporter gene assays. In...

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Main Authors: Maria Maddalena Calabretta, Antonia Lopreside, Laura Montali, Luca Cevenini, Aldo Roda, Elisa Michelini
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-01-01
Series:Sensors
Subjects:
bioluminescence
luciferase
complementation assay
3D cell model
androgen receptor
Online Access:https://www.mdpi.com/1424-8220/21/3/893
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