A comprehensive review on diabetic foot ulcer addressing vascular insufficiency, impaired immune response, and delayed wound healing mechanisms

Diabetic foot ulcers (DFUs) continue to represent one of the most significant and costly complications related to diabetes mellitus, posing serious challenges to healthcare systems and resulting in considerable morbidity rates. This narrative review explores the complex pathophysiology of DFUs, focu...

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Detalhes bibliográficos

Principais autores:	Chavan Aditya, Sarad Pawar Naik Bukke, Kuttiappan Anitha, Pandhare Meeraraje, Narayana Goruntla, Tadele Mekuriya Yadesa, Hope Onohuean
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-11-01
coleção:	Frontiers in Pharmacology
Assuntos:	diabetic foot ulcer immunological responses macrovascular contamination microvascular neuropathy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1622055/full
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