Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions

The current study was designed to formulate ternary solid dispersions (TSDs) of dexibuprofen (Dex) by solvent evaporation to augment the solubility and dissolution profile, in turn providing gastric protection and effective anti-inflammatory activity. Initially, nine formulations (S1 to S9) of binar...

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Detalles Bibliográficos

Principais autores:	Muhammad Asim, Marriam Nazir, Zunera Chauhdary, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Usra, Raed I. Felimban, Mohammed A Majrashi, Mohannad S. Hazzazi, Mohammed Alissa, Safa H Qahl, Ghulam Hussain, Azhar Rasul, Shahzad Ali Shahid Chatha, Ikram Ullah Khan
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-01-01
Series:	Pharmaceutics
Assuntos:	dexibuprofen solid dispersions Syloid 244FP<sup>®</sup>, Gelucire 48/16<sup>®</sup> and Poloxamer 188<sup>®</sup>
Acceso en liña:	https://www.mdpi.com/1999-4923/15/2/399
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