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Assessment of the efficacy and safety of two albendazole regimens for the treatment of hypermicrofilaraemic loiasis in adults in Woleu-Ntem Province, Gabon: A phase IIb single-blind randomised controlled trial.

<h4>Background</h4>Loa (L.) loa hypermicrofilaraemia (≥ 8,000 mf/mL) increases the risk of severe adverse events during mass ivermectin administration for onchocerciasis control. Albendazole has been proposed as a potential alternative for reducing microfilaraemia prior to ivermectin administration....

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Hauptverfasser: Noé Patrick M'Bondoukwé, Luccheri Ndong Akomezoghe, Bridy Chesly Moutombi Ditombi, Jacques Mari Ndong Ngomo, Hadry Roger Sibi Matotou, Ginette Severine Zang Ondo, Valentin Migueba, Coella Joyce Mihindou, Bedrich Pongui Ngondza, Christian Mayandza, Héléna Noéline Kono, Dimitri Ardin Moussavou Mabicka, Charleine Manomba, Reinne Moutongo, Luice Aurtin Joel James, Denise Patricia Mawili Mboumba, Marielle Karine Bouyou Akotet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2026-01-01
Schriftenreihe:PLoS Neglected Tropical Diseases
Online-Zugang:https://doi.org/10.1371/journal.pntd.0013166
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