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Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain

A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (HPMC) and sodium alginate (SA). The formulations w...

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Principais autores: Hussain Amjad, Syed Muhammad Ali, Abbas Nasir, Hanif Sana, Arshad Muhammad Sohail, Bukhari Nadeem Irfan, Hussain Khalid, Akhlaq Muhammad, Ahmad Zeeshan
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2016-06-01
coleção:Acta Pharmaceutica
Assuntos:
dental pain
mucoadhesion time
mucoadhesive strength
buccal tablet
artificial neural network
Acesso em linha:https://doi.org/10.1515/acph-2016-0020
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