Global mapping of RNA N6-methyladenosine (m6A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity

Abstract Background Obesity is a major health challenge and fat accumulation in visceral depots is more strongly associated with metabolic comorbidities than deposition in subcutaneous depots. Epitranscriptomic regulation of gene expression by N6-methyladenosine (m6A) influences various aspects of R...

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Ngā kaituhi matua:	Torunn Rønningen, Yong Zeng, Mai Britt Dahl, Junbai Wang, Tina Visnovska, Tone Møller Tannæs, Lars la Cour Poulsen, Akin Cayir, Stina Ingrid Alice Svensson, Marius Svanevik, Jens Kristoffer Hertel, Jøran Hjelmesæth, Jon A. Kristinsson, Tom Mala, Matthias Blüher, Housheng Hansen He, Tone Gretland Valderhaug, Yvonne Böttcher
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2025-11-01
Rangatū:	Biomarker Research
Ngā marau:	Obesity Fat distribution Adipose tissue N6-methyladenosine Epitranscriptomics
Urunga tuihono:	https://doi.org/10.1186/s40364-025-00857-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!