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Identification of Potent Inhibitors Targeting EGFR and HER3 for Effective Treatment of Chemoresistance in Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. Despite the existence of various therapeutic options, NSCLC is still a major health concern due to its aggressive nature and high mutation rate. Consequently, HER3 has been selected as a target protein along with EGFR because...

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Principais autores: Ayed A. Dera, Sumera Zaib, Areeba, Nadia Hussain, Nehal Rana, Hira Javed, Imtiaz Khan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-06-01
Serier:Molecules
Fag:
chemoresistance
epidermal growth factor receptor
HER3
lung cancer
pharmacophore design
Online adgang:https://www.mdpi.com/1420-3049/28/12/4850
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