NAMPT Inhibition Induces Neuroblastoma Cell Death and Blocks Tumor Growth

High-risk neuroblastoma (NB) portends very poor prognoses in children. Targeting tumor metabolism has emerged as a novel therapeutic strategy. High levels of nicotinamide-adenine-dinucleotide (NAD+) are required for rapid cell proliferation. Nicotinamide phosphoribosyl transferase (NAMPT) is the rat...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Frederic A. Vallejo, Anthony Sanchez, Branko Cuglievan, Winston M. Walters, Guillermo De Angulo, Steven Vanni, Regina M. Graham
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-06-01
Edice:	Frontiers in Oncology
Témata:	NAMPT (Nicotinamide Phosphoribosyltransferase) precision medicine neuroblastoma NAD metabolism Glycolysis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2022.883318/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!