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Parp3 assists muscle function and skeletal muscle differentiation by selectively adjusting H3K27me3 enrichment

Summary: Poly(ADP-ribose) polymerase 3 (Parp3) is known for its role in DNA repair, mitotic division, and cancer aggressiveness. Still, its physiological roles have yet to be defined. Here, we combined in vivo studies using Parp3-deficient mice with in cellulo studies to explore the involvement of P...

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Principais autores: Zuleyha Yildirim, Aurélia Noll, Kathline Martin-Hernandez, Jean-Christophe Amé, Najat Hanini, Nadia Messaddeq, Isabelle Robert, Bernardo Reina San Martin, Gunn Hildrestrand, Magnar Bjoras, Françoise Dantzer
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2025-04-01
סדרה:iScience
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גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2589004225005280
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