The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

Abstract Background Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease pathogenesis, including known risk factors for Alzheimer’s disease (AD), such as metabolic, cardiovascular, and cerebrovascular disea...

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Autors principals:	Nicholas M. Vogt, Kymberleigh A. Romano, Burcu F. Darst, Corinne D. Engelman, Sterling C. Johnson, Cynthia M. Carlsson, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin, Federico E. Rey
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-12-01
Col·lecció:	Alzheimer’s Research & Therapy
Matèries:	Alzheimer’s disease Cerebrospinal fluid Biomarkers Trimethylamine N-oxide Microbiota Gut bacteria
Accés en línia:	http://link.springer.com/article/10.1186/s13195-018-0451-2
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