Study of Validity of PC-3 Derived Xenograft Tumor Model in Athymic Nude Mice for Targeting Therapy of Androgen Receptors in Preclinical Studies of Prostate Cancer
Background: Androgen receptors (AR) play an important role in proliferation of cancerous prostatic cells and prevention of apoptotic signaling. Current drugs cannot inhibit the activity of these receptors very well. Establishment of appropriate animal models is essential for discovery of new drugs o...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tehran University of Medical Sciences
2016-10-01
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| coleção: | Basic & Clinical Cancer Research |
| Assuntos: | |
| Acesso em linha: | https://bccr.tums.ac.ir/index.php/bccrj/article/view/19 |
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