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A Multicenter, open-label, randomized, non-inferiority trial of 8 versus 12 weeks of sofosbuvir/ravidasvir treatment in non-cirrhotic patients with chronic hepatitis C virus infection (EASE trial)

Objective: To determine whether an 8-week regimen of sofosbuvir/ravidasvir is non-inferior to the standard 12-week regimen in non-cirrhotic chronic hepatitis C virus (HCV) infection. Design or Methods: We conducted a multicenter open-label, randomized, non-inferiority clinical trial across nine hosp...

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Principais autores: Muhammad Radzi Abu Hassan, Nor Asiah Muhamad, Noor Syahireen Mohammed, Mohd Azri Mohd Suan, Deanna Nadia Zulkifli Supramaniam, Sathya Rao Jogulu, Muhammad Firdaus Md Salleh, Shahrul Aiman Soelar, Izzah Athirah Rosli, Fatin Norhasny Leman, Nor Soleha Mohd Dali, Nur Hasnah Maamor, Nor Fariza Ngah, Huan-Keat Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-08-01
coleção:International Journal of Infectious Diseases
Assuntos:
Chronic hepatitis C
Antiviral agents
Sofosbuvir
Ravidasvir
Malaysia
Clinical trial
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1201971226004236
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