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GLRX2 polymorphism and oxidative stress levels impact urothelial bladder cancer outcomes

Abstract The bladder is continuously exposed to oxidative and mutagenic agents. Such chemicals are metabolized, filtered by the kidneys, and excreted in the urine. Not surprisingly, urothelial bladder cancer (UBC) is the 9th most common cancer worldwide. This study investigates whether the C > T (rs...

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Autores principales: Isabely M. Silva, Beatriz G. L. Vacario, Flora T. Maraslis, Alexsandro Koike, Maria E. P. Simonato, Carolina Coradi, Alvaro J. Fernandes, Andréa N. C. Simão, Marcell A. B. Lozovoy, Gustavo R. M. Barcelos, Mateus L. Falco, Roberta Losi Guembarovski, Carolina Panis, Juliana Mara Serpeloni
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2025-09-01
Colección:Scientific Reports
Materias:
GRX2
Urothelial bladder cancer
Oxidative stress
Recurrence
Acceso en línea:https://doi.org/10.1038/s41598-025-12587-2
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